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Michael P. DeFrain, MD

Thoracic Surgery, General Surgery

Provider Rating



199 reviews

Visit Preparation: 4.8
Patient Recomm...: 4.8
Provider Explan...: 3.9
Office Wait Time: 4.3

Cardiac Surgical Associates of Northside

6006 49th Street North, Suite 310
St. Petersburg, FL 33709

About Michael P. DeFrain

Michael Patrick DeFrain, MD was born and raised in East Lansing, Michigan. After completing his undergraduate degree at the University of Michigan, he was awarded his medical degree from Wayne State University. His general surgery residency was also completed in Michigan at Michigan State University. Dr. DeFrain then moved to Texas to attend the Texas Heart Institute for his cardiothoracic surgery residency. While there, Dr. DeFrain had the privilege of training and operating with the world-renowned heart surgeon, Dr. Denton Cooley. He has extensive training in minimally invasive valve surgery and mitral valve repair. His professional focus is centered on efforts to develop new techniques that utilize the least invasive methods to accomplish coronary bypass, valve repair, and other heart operations.

Dr. DeFrain believes that the best surgical results are achieved when operative techniques are simplified with the least possible physical impact on the patient. Dr. DeFrain is a diplomat of the American Board of Surgery and the American Board of Thoracic Surgery. His professional memberships include: The Denton A. Cooley Cardiovascular Surgical Society, The Society of Thoracic Surgeons, The Southern Thoracic Surgical Association and The American College of Surgeons.

Dr. DeFrain is deeply committed to his patients and their families. In his free time, Dr. DeFrain enjoys kite surfing and spending weekends at the beach in Florida, or the lakes of Michigan with his wife Stephanie and their three children.


Medical School
Wayne State University School of Medicine

Michigan State University, Texas Heart Institute



Languages Spoken


Procedures & Conditions


  • Coronary Artery Bypass Graft Surgery (CABG)
  • Minimally Invasive Heart Surgery
  • Robotic
  • Transcatheter Aortic Valve Replacement (TAVR)
  • Valves
  • Video-Assisted Thoracic Surgery (VATS)


  • Coronary Artery Disease
  • Heart Attack and Chest Pain (Angina)
  • Peripheral Artery Disease
  • Peripheral Vascular Disease
  • Stroke
  • Valve Disease (including aortic stenosis and mitral valve disease)


Thoracic Surgery
General Surgery

Office Locations

Cardiac Surgical Associates of Northside
6006 49th Street North
Suite 310
St. Petersburg, FL 33709
Phone: (727) 527-9779
Fax: (727) 522-0415

Office Hours

Mon - Fri
8:00am - 4:00pm

Accepted Insurance

  • Cigna
  • Humana
  • Medicaid
  • Wellcare